spb/cancerindex

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Fri, Sep 11, 2026 10
1. Biomarkers: 54 NCIt-verified canonical biomarkers (seed), /biomarkers and /biomarker/[slug] with derived links, /v1/biomarkers API, methodology, sitemap, nav; fix silent failure of the trials 'active' status filter (array param inside ANY)
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +115
2. openFDA: shared parent/child aliases resolve to the broadest concept (fixes 67 approvals mapped to childhood entities), backfill supersedes edges no longer asserted; RawLake.read returns null on a missing file instead of hanging the process
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +11
3. EMA connector: medicines data xlsx (exceljs), oncology scope by ATC/MeSH/indication, EU approval rows with authorisation dates and statuses, indication-text cancer mapping, APPROVED_FOR edges, drug codes, fixtures and tests
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +217
4. Regulatory layer: Health Canada DPD connector (ATC L01/L02/L03/V10, DIN-level approval records, drug minting + codes), /approvals feed, drug development pipeline (drug_pipeline) with /pipeline, duplicate-drug merge proposals, drug page identifiers/pipeline, API
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 2 files +253
5. Integration: home modules (explorer, trial intelligence, map, graph), graph links on entity pages, gap card on cancer rankings tab, methodology sections, API docs, QA routes
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 2 files +31
6. Knowledge graph: contextual neighbourhoods (source-native edges + derived registry links), radial SVG explorer /graph, cancer→gene→variant→drug→approval→trial paths, /v1/graph API, methodology
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +153
7. Data explorer: /explore (metric × cancers × geography × sex × age × years → comparable chart groups + table + CSV/JSON/permalink), coverage matrix, /v1/epidemiology API, methodology
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +115
8. Clinical trial intelligence: per-cancer trial metrics (growth, enrollment, sponsor/country HHI, termination share, burden-normalized), stop-reason classifier, 4 ranking snapshots, /trials/intelligence and /trials/terminated, API, CSV, cancer tab strip
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +192
9. Clinical trial map: country site aggregates (trial_site_country_counts), ISO mapping, Equal Earth choropleth, /trials/map, /v1/trials/sites, methodology
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +49
10. Research Gap Index: components table, share/log2-ratio metrics, per-1000-deaths snapshots, /research-gap page with log-log scatter, API, CSV export, methodology
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +149
Tue, Sep 8, 2026 5
1. Resolver: byCode carries recorded match types (alias/lineage codes); MeSH/ChEMBL docs
  
  Simon-Pierre Boucher 2 mo ago · 1 file +19 −2
2. Web: paginate approvals and gene cohort tables
  
  Simon-Pierre Boucher 2 mo ago · 1 file +16 −2
3. SDK HttpClient: body-read timeout with retry (stalled ChEMBL responses)
  
  Simon-Pierre Boucher 2 mo ago · 2 files +27 −5
4. Wave 2: SDK checkpoints/abort/anomaly guard/alerts, cix doctor, backups, perf indexes, migration 0001; MeSH, ChEMBL, openFDA, cBioPortal connectors; web pagination/QA/tests/caching, countries, compare, key figures; USCS sex-specific rate fix
  
  Simon-Pierre Boucher 2 mo ago · 8 files +575
5. Phase 1: NCIt/OncoTree/HGNC/CIViC/ClinVar/GDC/ClinicalTrials/PubMed/CDC WONDER connectors, ranking engine, Fastify API, pg-boss worker, Next.js web app, docs, deploy
  
  Simon-Pierre Boucher 2 mo ago · 25 files +10,916