spb/cancerindex

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Fri, Sep 11, 2026 10
1. Site identity: author Simon-Pierre Boucher, contact@spboucher.ai, hosted on MacLustr (www.maclustr.io) in footer, About, methodology, metadata and OpenAPI contact
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +1 −1
2. Biomarkers: 54 NCIt-verified canonical biomarkers (seed), /biomarkers and /biomarker/[slug] with derived links, /v1/biomarkers API, methodology, sitemap, nav; fix silent failure of the trials 'active' status filter (array param inside ANY)
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 2 files +233
3. Regulatory layer: Health Canada DPD connector (ATC L01/L02/L03/V10, DIN-level approval records, drug minting + codes), /approvals feed, drug development pipeline (drug_pipeline) with /pipeline, duplicate-drug merge proposals, drug page identifiers/pipeline, API
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +208 −5
4. Knowledge graph: contextual neighbourhoods (source-native edges + derived registry links), radial SVG explorer /graph, cancer→gene→variant→drug→approval→trial paths, /v1/graph API, methodology
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +620 −5
5. Data explorer: /explore (metric × cancers × geography × sex × age × years → comparable chart groups + table + CSV/JSON/permalink), coverage matrix, /v1/epidemiology API, methodology
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +207 −5
6. Clinical trial intelligence: per-cancer trial metrics (growth, enrollment, sponsor/country HHI, termination share, burden-normalized), stop-reason classifier, 4 ranking snapshots, /trials/intelligence and /trials/terminated, API, CSV, cancer tab strip
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +184 −5
7. Clinical trial map: country site aggregates (trial_site_country_counts), ISO mapping, Equal Earth choropleth, /trials/map, /v1/trials/sites, methodology
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 2 files +110
8. Research Gap Index: components table, share/log2-ratio metrics, per-1000-deaths snapshots, /research-gap page with log-log scatter, API, CSV export, methodology
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 1 file +129 −4
9. Split research-gap routes, trial-sites stub, unit labels for new metrics
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 3 files +17 −13
10. Foundation for wave 3: intelligence schema (trial_intelligence, trial_site_country_counts, drug_pipeline, drug_codes, research_gap_components; migration 0002), trial intervention→drug reconciliation (alias/salt-stripped/probabilistic), new metric definitions (trial growth, termination share, sponsor HHI, per-1000-deaths, gap ratios), maintenance.intel job, API route stubs (epidemiology/approvals/graph/intelligence), navigation restructure
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  Co-Authored-By: Claude Fable 5.1 <noreply@anthropic.com>
  Simon-Pierre Boucher 1 mo ago · 6 files +61
Tue, Sep 8, 2026 2
1. Wave 2: SDK checkpoints/abort/anomaly guard/alerts, cix doctor, backups, perf indexes, migration 0001; MeSH, ChEMBL, openFDA, cBioPortal connectors; web pagination/QA/tests/caching, countries, compare, key figures; USCS sex-specific rate fix
  
  Simon-Pierre Boucher 2 mo ago · 1 file +8
2. Phase 1: NCIt/OncoTree/HGNC/CIViC/ClinVar/GDC/ClinicalTrials/PubMed/CDC WONDER connectors, ranking engine, Fastify API, pg-boss worker, Next.js web app, docs, deploy
  
  Simon-Pierre Boucher 2 mo ago · 28 files +2,160